MEDICATIONS CONTRAINDICATED IN PREGNANCY

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1. Vitamin A and its derivatives (isotretinein, Accutane and etretinate)Women who are pregnant should not take regular vitamins. Too many vitamins can harm your baby. For example, very high levels of vitamin A have been linked with severe birth defects.Significant risk of spontaneous abortion [20] and risk of many significant anomalies2. ACE inhibitors (May cause fetal hypotension, kidney damage in the fetus when used in II and III trimester, decrease in the amount of amniotic fluid and deformities of face, limbs and lungs)3. Anticoagulants- warfarinDuring 1st Trimester- defects like nasal hypoplasia and a depressed nasal bridge; termed as Fetal warfarin SyndromeDuring 2nd and 3rd Trimester- risk of fetal malformations
4. Anti-thyroids (Methimazole, Carbimazole) - Overactive and enlarged Thyroid gland.
5. Anticonvulsants- Carbamazepine (Risk of birth defects)
                                 Sodium valproate (Increased risk cleft palate and abnormalities of the heart, face, skull, hands or abdominal organs)6. NSAIDs     Aspirin and other Salicylates  Delay in start of labor, premature closing of ductus arteriosus, jaundice, brain damage in the fetus and bleeding problems in the woman during and after delivery and in the newbornCan cause serious blood flow problems in the baby if used during the last 3 months of pregnancy7. Ciprofloxacin          Possibility of joint abnormalities8. Kanamycin and Streptomycin        Damage to fetus's ear resulting in deafness (risk of ototoxicity9. Oral Hypoglycemic drugs   A very low level of sugar in the blood of newborn.


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