MEDICATIONS CONTRAINDICATED IN PREGNANCY
1. Vitamin A and its derivatives (isotretinein, Accutane and etretinate) Women who are pregnant should not take regular vitamins. Too many vitamins can harm your baby. For example, very high levels of vitamin A have been linked with severe birth defects. Significant risk of spontaneous abortion [20] and risk of many significant anomalies 2. ACE inhibitors (May cause fetal hypotension, kidney damage in the fetus when used in II and III trimester, decrease in the amount of amniotic fluid and deformities of face, limbs and lungs) 3. Anticoagulants- warfarin During 1 st Trimester- defects like nasal hypoplasia and a depressed nasal bridge; termed as Fetal warfarin Syndrome During 2 nd and 3 rd Trimester- risk of fetal malformations 4. Anti-thyroids (Methimazole, Carbimazole) - Overactive and enlarged Thyroid gland. 5. Anticonvulsants- Carbamazepine (Risk of birth defects) Sodium valproate (Increased risk cleft palate and abnormalities of the heart,