Alprazolam

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Indications:
  • Treating anxiety and panic disorder.

Do NOT use Alprazolam if:

  • you are allergic to any ingredient in Alprazolam or other benzodiazepines (eg, diazepam)
  • you have acute narrow-angle glaucoma, severe liver disease, or a mental state where contact with reality is lost (psychosis)
  • you are taking an azole antifungal (eg, itraconazole, ketoconazole), delavirdine, or sodium oxybate (GHB)

Before using Alprazolam :
Some medical conditions may interact with Alprazolam . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines or other substances
  • if you have glaucoma or a predisposition for glaucoma, liver problems, lung problems or chronic obstructive pulmonary disease (COPD), muscle problems, depression, suicidal tendencies, a blood disorder known as porphyria, or a history of substance abuse or dependence

Drug Interactions:

  • Rifampin or St. John's wort because the effectiveness of Alprazolam may be decreased
  • Azole antifungals (eg, itraconazole, ketoconazole), cimetidine, clozapine, delavirdine, fluvoxamine, HIV protease inhibitors (eg, ritonavir), fluoxetine, macrolides and ketolides (eg, erythromycin, azithromycin), nefazodone, omeprazole, propoxyphene, sodium oxybate (GHB), or valproic acid because side effects such as increased sedation or heart problems may occur.
  • Clozapine, hydantoins (eg, phenytoin), or valproic acid because the actions and side effects of these medicines may be increased.

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